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Current Publications

 

Kennedy PH, Sheikh AAD, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer C, Alarcón S, Newby G, Myers SA. 2023. Proteome-wide base editor screens to assess phosphorylation site functionality in high-throughput. bioRxiv 2023.11.11.566649. doi: https://doi.org/10.1101/2023.11.11.566649

Larange A, Takazawa A, Kakugawa K, Thiault N, Ngoi SM, Olive ME, Iwaya H,  Seguin L, Vicente-Suarez I, Becart S, Verstichel G, Balancio A, Altman A, Chang JT, Taniuchi I, Lillemeier B,  Kronenberg M, Myers SA, and Cheroutre H. T Cell Activation is Spatially and Temporally Controlled by Extranuclear and Nuclear RARα. Immunity, 56:2054-2069, 2023.

Rios-Covian D, Butcher LD, Ablack AL, den Hartog G, Matsubara MT, Ly H, Oates AW, Xu G, Fisch KM, Ahrens ET, et al. 2023. A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells. Antioxidants & Redox Signaling. 38(1-3). doi:https://doi.org/10.1089/ars.2021.0119.

Saddawi-Konefka R, O’Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang N-A, et al. 2022. Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC. Nature Communications. 13(1). doi:https://doi.org/10.1038/s41467-022-31941-w.

Umemoto S, Nakahashi-Ouchida R, Yuki Y, Kurokawa S, Machita T, Uchida Y, Mori H, Yamanoue T, Shibata T, Sawada S, et al. 2023. Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents. PJ Vaccines. 8(1). doi:https://doi.org/10.1038/s41541-023-00700-3.

Zhang Z, Ernst PB, Kiyono H, Kurashima Y. 2022. Utilizing mast cells in a positive manner to overcome inflammatory and allergic diseases. Frontiers in Immunology. 13(13). doi:https://doi.org/10.3389/fimmu.2022.937120.

Zhang Z, Tanaka I, Pan Z, Ernst PB, Kiyono H, Kurashima Y. 2022. Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis. European Journal of Immunology. 52(7). doi:https://doi.org/10.1002/eji.202149532.

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Barajas-Mora, EM, Lee L, Lu H, J. Andrés Valderrama, Elisabet Bjånes, Nizet V, Feeney AJ, Hu M, Cornelis Murre. 2023. Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens. Nature Immunology. 24(2):320–336. doi:https://doi.org/10.1038/s41590-022-01402-z. 

Dong J-Y, Huth WJ, Marcel N, Zhang Z, Lin L-L, Lu L-F. 2023. miR-15/16 clusters restrict effector Treg cell differentiation and function. Journal of Experimental Medicine. 220(10). doi:https://doi.org/10.1084/jem.20230321. [accessed 2023 Oct 16]. https://rupress.org/jem/article-abstract/220/10/e20230321/276135/miR-15-16-clusters-restrict-effector-Treg-cell?redirectedFrom=fulltext. 

Du L, Ji Y, Bing X, Zhang J, Lu L, Glass CK, Feng G. 2023. Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages. Cellular and Molecular Gastroenterology and Hepatology. 15(6):1351–1369. doi:https://doi.org/10.1016/j.jcmgh.2023.02.011. 

Jang, HJ, Caron C, Lee CK, Wang L, Jama B, Bui JD, Morris GP. 2023. Dual receptor T cells mediate effective antitumor immune responses via increased recognition of tumor antigens. Journal for ImmunoTherapy of Cancer. 11(5):e006472–e006472. doi:https://doi.org/10.1136/jitc-2022-006472. [accessed 2023 Oct 16]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186424/. 

Kaneko K, Liang Y, Liu Q, Chen WS, Feng G. 2022 May 17. Identification of CD133+Intercellsomes in Intercellular Communication to Offset Intracellular Signal Deficit. bioRxiv (Cold Spring Harbor Laboratory). doi:https://doi.org/10.1101/2022.05.16.492226. 

Larange A, Takazawa I, Kakugawa K, Thiault N, Ngoi S, Olive ME, Iwaya H, Seguin L, Vicente-Suarez I, Becart S, et al. 2023a. A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function. Immunity. 56(9):2054-2069.e10. doi:https://doi.org/10.1016/j.immuni.2023.07.017. [accessed 2023 Oct 16]. https://www.sciencedirect.com/science/article/pii/S1074761323003308#ack0010. 

Lin, YH, Duong HG, Limary AE, Kim ES, Hsu P, Patel SA, Wong WH, Indralingam CS, Yi Chia Liu, Yao P, et al. 2023. Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes. Immunity. 56(1):207-223.e8. doi:https://doi.org/10.1016/j.immuni.2022.12.007. 

Liu JJ, Bing X, Du L, Chen LY, Long Y, Feng G. 2023. Pharmaceutical SH2 domain–containing protein tyrosine phosphatase 2 inhibition suppresses primary and metastasized liver tumors by provoking hepatic innate immunity. Hepatology. 77(5):1512–1526. doi:https://doi.org/10.1002/hep.32555. 

Riffelmacher T, Paynich Murray M, Wientjens C, Chandra S, Cedillo-Castelán V, Chou T-F, McArdle S, Dillingham C, Devereaux J, Nilsen A, et al. 2023. Divergent metabolic programmes control two populations of MAIT cells that protect the lung. Nature Cell Biology. 25(6):1–15. doi:https://doi.org/10.1038/s41556-023-01152-6. [accessed 2023 May 26]. https://www.nature.com/articles/s41556-023-01152-6. 

Sulczewski FB, Maqueda-Alfaro RA, Alcántara-Hernández M, Perez OA, Saravanan S, Yun TJ, Seong D, Arroyo Hornero R, Raquer-McKay HM, Esteva E, et al. 2023. Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses. Nature Immunology. 24(8):1265–1280. doi:https://doi.org/10.1038/s41590-023-01545-7. [accessed 2023 Oct 16]. https://pubmed.ncbi.nlm.nih.gov/37414907/. 

Tsu BV, Agarwal R, Gokhale NS, Kulsuptrakul J, Ryan AP, Castro LK, Beierschmitt C, Turcotte E, Fay EJ, Vance RE, et al. 2022. Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome. bioRxiv (Cold Spring Harbor Laboratory). 45(11). doi:https://doi.org/10.1101/2022.09.21.508960. 

Vladimir Lažetić, Batachari LE, Russell AD, Troemel ER. 2023. Similarities in the induction of the intracellular pathogen response in Caenorhabditis elegans and the type I interferon response in mammals. BioEssays. 45(11). doi:https://doi.org/10.1002/bies.202300097. 

Wang K-C, Eziz Kuliyev, Nizet V, Ghosh P. 2023. A conserved three-dimensional pattern in a Streptococcus pyogenes M protein immunogen elicits M type cross-reactivity. Journal of Biological Chemistry. 299(8):104980–104980. doi:https://doi.org/10.1016/j.jbc.2023.104980. 

Wu VH, Yung BS, Faraji F, Saddawi‐Konefka R, Wang Z, Wenzel AT, Song M, Meghana Pagadala, Clubb LM, Chiou J, et al. 2023. The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nature Immunology. 24(8):1318–1330. doi:https://doi.org/10.1038/s41590-023-01529-7. 

Xu X, Dennett P, Zhang J, Sherrard A, Zhao Y, Takeya Masubuchi, Bui JD, Chen X, Hui E. 2023. CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis. Journal of Experimental Medicine. 220(7). doi:https://doi.org/10.1084/jem.20221391. 

Zhao Y, Caron C, Chan Y-Y, Lee CK, Xu X, Zhang J, Takeya Masubuchi, Wu C, Bui JD, Hui E. 2023. cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity. Immunity. 56(6):1187-1203.e12. doi:https://doi.org/10.1016/j.immuni.2023.04.005.