Publication Spotlight

Chandra S., Ascui G., Riffelmacher T., Chawla A., Ramírez-Suástegui C., Castelan V.C., Seumois, G., Simon, H., Murray M.P., Seo, G.-Y., Premlal A.L.R., Schmiedel, B., Verstichel G., Li, Y., Lin, C.-H., Greenbaum, J., Lamberti, J., Murthy R., Nigro, J., Cheroutre, H., Ottensmeier, C.H., Hedrick, S.M., Lu, L.-F., Vijayanand, P., and Kronenberg, M.  Transcriptomes and metabolism define mouse and human MAIT cell populations. Science Immunology, 8: 10.1126/sciimmunol.abn8531, 2023.

Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nat Immunol. 2023 Aug;24(8):1318-1330. doi: 10.1038/s41590-023-01529-7. Epub 2023 Jun 12. PMID: 37308665.

Baghdassarian H, Blackstone SA, Owen Scott Clay, Rachael Laura Philips, Brynja Matthiasardottir, Nehrebecky M, Hua V, McVicar RN, Liu Y, Tucker S, et al. 2023. Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome. The New England Journal of Medicine. 388(24):2241–2252. doi:https://doi.org/10.1056/nejmoa2202318.